seek to pioneer new approaches Preliminary studies hint novel algorithms predictive models software tools for integrative analysis and visualization of genetic interaction networks to facilitate discovery developing new computational biology graduate level highly collaborative, interdisciplinary projects Analysis & Interpretation Using a systems biology approach The methods will be tested and validated in a number of real biological problems enticing them to pursue careers in science web-based tools in silico knockouts drug intervention can be seen as control of cellular network activity verification methods to check whether a model is consistent with the laboratory experimental observations on which it is based If the model does not conform to the data, we suggest a revised model and the new hypotheses are tested in-silico. The hypotheses formulated during in-silico testing suggest new avenues to explore experimentally. emerging field of System